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KMID : 0931320120120040265
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대한상부위장관.헬리코박터학회지
2012 Volume.12 No. 4 p.265 ~ p.270
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Two Cases of Gastric MALT Lymphoma Diagnosed at Long Last afterSuccessful Eradication of Helicobacter pylori
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yeom Soo-Jeong
Lee In-Seok
Cho Seok-Goo
Choi Myung-Gyu
Choi Gyu-Yong
Park Gyeong-Sin
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Abstract
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The gastric marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) is a rare disease. Helicobacter pylori infection is known as an important etiologic factor of the pathogenesis of MALT lymphoma. H. pylori colonization at the epithelium of gastric mucosa induces T cell and B cell recruitment. T cell induced B cell proliferation develops the MALT in the gastric mucosa. Monoclonal proliferation of B cell in the MALT transform into MALT lymphoma. The eradication of H. pylori is known to induce remission of the disease in more than 80% of patients. But there is no report on progression and development of MALT lymphoma after H. pylori eradication. We experienced two cases of gastric B cell MALT lymphoma diagnosed at long last, after the successful eradication of H. pylori.
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KEYWORD
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Helicobacter pylori, MALT lymphoma, Eradication
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